SOX2 anticorps (AA 227-317) (Alexa Fluor 350)

N° du produit ABIN916101

Détail du produit anti-SOX2 anticorps (Alexa Fluor 350)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Épitope: AA 227-317

Reactivité: Humain, Souris, Rat, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX2 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Chévre, Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2 (SOX2 Produits)

Synonymes: anticorps ANOP3, anticorps MCOPS3, anticorps RGD1565646, anticorps Sox-2, anticorps lcc, anticorps ysb, anticorps cb236, anticorps wu:fb83g04, anticorps wu:fc14d07, anticorps zgc:65860, anticorps zgc:77389, anticorps SRY-box2, anticorps Xsox-2, anticorps anop3, anticorps mcops3, anticorps sox-2, anticorps SRY-box 2, anticorps SRY box 2, anticorps SRY (sex determining region Y)-box 2, anticorps SRY-box 2 S homeolog, anticorps SOX2, anticorps Sox2, anticorps sox2, anticorps sox2.S

Sujet:

Synonyms: lcc, ysb, Sox-2, Transcription factor SOX-2, Sox2

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

ID gène: 20674

UniProt: P48432

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis