TRPV4 anticorps (AA 301-400) (FITC)
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- Antigène Voir toutes TRPV4 Anticorps
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
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Épitope
- AA 301-400
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Reactivité
- Humain, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRPV4 est conjugé à/à la FITC
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Boeuf (Vache), Humain
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human TRPV4
- Isotype
- IgG
- Top Product
- Discover our top product TRPV4 Anticorps primaire
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- Indications d'application
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
- Autre désignation
- TRP12 (TRPV4 Produits)
- Synonymes
- anticorps wu:fp52e02, anticorps CMT2C, anticorps HMSN2C, anticorps OTRPC4, anticorps SMAL, anticorps SPSMA, anticorps SSQTL1, anticorps TRP12, anticorps VRL2, anticorps VROAC, anticorps 0610033B08Rik, anticorps Trp12, anticorps VR-OAC, anticorps VRL-2, anticorps Otrpc4, anticorps Vroac, anticorps transient receptor potential cation channel, subfamily V, member 4, anticorps transient receptor potential cation channel subfamily V member 4, anticorps trpv4, anticorps TRPV4, anticorps Trpv4
- Sujet
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Synonyms: SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1, Transient receptor potential cation channel subfamily V member 4, TrpV4, Osm-9-like TRP channel 4, Transient receptor potential protein 12, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, VRL-2, Vanilloid receptor-related osmotically-activated channel, VR-OAC
Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH , citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
- ID gène
- 59341
- UniProt
- Q9HBA0
- Pathways
- Hormone Transport, Cell-Cell Junction Organization
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