TNFRSF10A anticorps (C-Term)

N° du produit ABIN925993

Détail du produit anti-TNFRSF10A anticorps

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF10A est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: TNFRSF10 A antibody was raised in rabbit using the C terminal of TNFRSF10 as the immunogen

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TNFRSF10A Blocking Peptide, catalog no. 33R-7807, is also available for use as a blocking control in assays to test for specificity of this TNFRSF10A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TNFRSF10A

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Autre désignation: TNFRSF10A (TNFRSF10A Produits)

Synonymes: anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798

Sujet: This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Synonyms: Polyclonal TNFRSF10A antibody, Anti-TNFRSF10A antibody, tumor necrosis factor receptor superfamily, member 10a antibody.

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity