PAI1 anticorps

N° du produit ABIN926100

Détail du produit anti-PAI1 anticorps

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Veuillez nous consulter SVP

Purification: Affinity chromatography purified

Immunogène: PAI1 antibody was raised in sheep using Recombinant Plasminogen Activator Inhibitor-1 prepared from bacterial extracts as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50 % (v/v) glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.

Stock: -20 °C

Stockage commentaire: Store at -10 to -20 °C.

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: PAI1 (SERPINE1 Produits)

Synonymes: anticorps PAI, anticorps PAI-1, anticorps PAI1, anticorps PLANH1, anticorps SERPINE1, anticorps si:ch211-138a11.1, anticorps Planh1, anticorps PAI1A, anticorps Pai1, anticorps Pai1aa, anticorps Planh, anticorps RATPAI1A, anticorps serpin family E member 1, anticorps serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog, anticorps serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, anticorps serine (or cysteine) peptidase inhibitor, clade E, member 1, anticorps SERPINE1, anticorps serpine1.L, anticorps serpine1, anticorps Serpine1

Sujet: PAI1 is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases. Synonyms: Polyclonal PAI1 antibody, Anti-PAI1 antibody, PAI-1 antibody, Plasminogen Activator Inhibitor-1 antibody, Serpin E1 antibody.

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration