PCSK2 anticorps (Middle Region)

N° du produit ABIN929268

Détail du produit anti-PCSK2 anticorps

Antigène: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK2 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: PCSK2 antibody was raised in rabbit using the middle region of PCSK2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PCSK2 Blocking Peptide, catalog no. 33R-4799, is also available for use as a blocking control in assays to test for specificity of this PCSK2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PCSK2

Antigène: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Autre désignation: PCSK2 (PCSK2 Produits)

Synonymes: anticorps NEC 2, anticorps NEC-2, anticorps NEC2, anticorps PC2, anticorps SPC2, anticorps PCSK2, anticorps 6330411F23Rik, anticorps AI839700, anticorps Nec-2, anticorps Nec2, anticorps Phpp-2, anticorps pc2, anticorps nec2, anticorps spc2, anticorps pcsk2, anticorps pcsk2-A, anticorps proprotein convertase subtilisin/kexin type 2, anticorps proprotein convertase subtilisin/kexin type 2 L homeolog, anticorps PCSK2, anticorps pcsk2, anticorps Pcsk2, anticorps pcsk2.L

Sujet: This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Synonyms: Polyclonal PCSK2 antibody, Anti-PCSK2 antibody, proprotein convertase subtilisin/kexin type 2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody.

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity