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COCH anticorps (N-Term)

COCH Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN929280
  • Antigène Voir toutes COCH Anticorps
    COCH (Cochlin (COCH))
    Épitope
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 2
    Lapin
    Clonalité
    • 48
    Polyclonal
    Conjugué
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COCH est non-conjugé
    Application
    • 37
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Purification
    Purified
    Immunogène
    COCH antibody was raised in rabbit using the N terminal of COCH as the immunogen
    Top Product
    Discover our top product COCH Anticorps primaire
  • Indications d'application
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    COCH Blocking Peptide, catalog no. 33R-1253, is also available for use as a blocking control in assays to test for specificity of this COCH antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Antigène
    COCH (Cochlin (COCH))
    Autre désignation
    COCH (COCH Produits)
    Synonymes
    anticorps AW122937, anticorps Coch-5B2, anticorps D12H14S564E, anticorps COCH-5B2, anticorps COCH5B2, anticorps DFNA9, anticorps cochlin, anticorps Coch, anticorps COCH
    Sujet
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. Synonyms: Polyclonal COCH antibody, Anti-COCH antibody, coagulation factor C homolog, cochlin, Limulus polyphemus antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody.
    Pathways
    Sensory Perception of Sound
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