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CD22 anticorps (C-Term)

CD22 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN929370
  • Antigène Voir toutes CD22 Anticorps
    CD22 (CD22 Molecule (CD22))
    Épitope
    • 16
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 153
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 101
    • 61
    • 14
    Lapin
    Clonalité
    • 124
    • 54
    Polyclonal
    Conjugué
    • 81
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD22 est non-conjugé
    Application
    • 111
    • 71
    • 45
    • 38
    • 38
    • 18
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogène
    CD22 antibody was raised in rabbit using the C terminal of CD22 as the immunogen
    Top Product
    Discover our top product CD22 Anticorps primaire
  • Indications d'application
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    CD22 Blocking Peptide, catalog no. 33R-10236, is also available for use as a blocking control in assays to test for specificity of this CD22 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Antigène
    CD22 (CD22 Molecule (CD22))
    Autre désignation
    CD22 (CD22 Produits)
    Synonymes
    anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
    Sujet
    CD22 mediates B-cell B-cell interactions. CD22 may be involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins, one of which is CD45. CD22 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response CD22 seems to be involved in regulation of B-cell antigen receptor signaling. CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Synonyms: Polyclonal CD22 antibody, Anti-CD22 antibody, CD22 molecule antibody, FLJ22814 antibody, MGC130020 antibody, SIGLEC-2 antibody, SIGLEC2 antibody.
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