SORL1 anticorps (AA 2159-2214)

N° du produit ABIN931367

Détail du produit anti-SORL1 anticorps

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Épitope: AA 2159-2214

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SORL1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: SORL1 antibody was raised in Mouse using a purified recombinant fragment of SORL1(aa2159-2214) expressed in E. coli as the immunogen.

Clone: 7D7B11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Détails sur SORL1

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Autre désignation: SORL1 (SORL1 Produits)

Synonymes: anticorps SORL1, anticorps C11orf32, anticorps LR11, anticorps LRP9, anticorps SORLA, anticorps SorLA-1, anticorps gp250, anticorps SorLA, anticorps 2900010L19Rik, anticorps AI596264, anticorps AW261561, anticorps mSorLA, anticorps Lr11, anticorps RGD619914, anticorps sortilin related receptor 1, anticorps sortilin-related receptor, anticorps sortilin-related receptor, L(DLR class) A repeats containing, anticorps sortilin-related receptor, L(DLR class) A repeats-containing, anticorps sortilin-related receptor, LDLR class A repeats-containing, anticorps sorl1, anticorps LOC582560, anticorps SORL1, anticorps Sorl1

Sujet: SORL1 is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. Synonyms: Monoclonal SORL1 antibody, Anti-SORL1 antibody, Sortilin related receptor L A repeats containing antibody.

Pathways: Smooth Muscle Cell Migration