TLR1 anticorps (N-Term)

N° du produit ABIN951276

Détail du produit anti-TLR1 anticorps

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Purified

Immunogène: Peptide corresponding to 16 amino acids near the amino terminus of human TLR1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur TLR1

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Autre désignation: CD281 / TLR1 (TLR1 Produits)

Synonymes: anticorps CD281, anticorps TIL, anticorps TIL. LPRS5, anticorps rsc786, anticorps toll like receptor 1, anticorps toll-like receptor 1, anticorps TLR1, anticorps Tlr1

Sujet: Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is coexpressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7).Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

ID gène: 9606

UniProt: Q15399

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades