IRF4 anticorps (Middle Region)

N° du produit ABIN952951

Détail du produit anti-IRF4 anticorps

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Épitope: AA 171-199, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human IRF4 (Center).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4 (IRF4 Produits)

Synonymes: anticorps LSIRF, anticorps MUM1, anticorps NF-EM5, anticorps AI385587, anticorps IRF-4, anticorps Spip, anticorps IRF4, anticorps si:ch73-170d1.2, anticorps irf4, anticorps interferon regulatory factor 4, anticorps interferon regulatory factor 4a, anticorps Interferon regulatory factor 4, anticorps PWWP domain-containing protein MUM1, anticorps IRF4, anticorps Irf4, anticorps irf4a, anticorps irf4, anticorps LOC612320, anticorps LOC100068881

Sujet: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5

Poids moléculaire: 51772 Da

ID gène: 3662

NCBI Accession: NP_001182215

Pathways: Chromatin Binding