KCNQ3 anticorps (C-Term)

N° du produit ABIN953015

Détail du produit anti-KCNQ3 anticorps

Antigène: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Épitope: AA 650-679, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse KCNQ3 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 650-679 amino acids from the C-terminal region of human KCNQ3

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KCNQ3

Antigène: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Autre désignation: KCNQ3 (KCNQ3 Produits)

Synonymes: anticorps KCNQ3, anticorps si:ch211-66b9.3, anticorps BFNC2, anticorps EBN2, anticorps KV7.3, anticorps potassium voltage-gated channel subfamily Q member 3, anticorps potassium voltage-gated channel, KQT-like subfamily, member 3, anticorps potassium voltage-gated channel, subfamily Q, member 3, anticorps KCNQ3, anticorps kcnq3, anticorps Kcnq3

Sujet: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).Synonyms: KQT-like 3, Potassium channel subunit alpha KvLQT3, Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3

Poids moléculaire: 96742 Da

ID gène: 3786

NCBI Accession: NP_001191753