PIGA anticorps (C-Term)

N° du produit ABIN954134

Détail du produit anti-PIGA anticorps

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Épitope: AA 147-177, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIGA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes PIGA at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 147-177aa) of human PIGA.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PIGA

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Autre désignation: PIGA (PIGA Produits)

Synonymes: anticorps GPI3, anticorps MCAHS2, anticorps PIG-A, anticorps AI194334, anticorps Pig-a, anticorps im:6911675, anticorps zgc:56589, anticorps phosphatidylinositol glycan anchor biosynthesis class A, anticorps phosphatidylinositol glycan anchor biosynthesis, class A, anticorps PIGA, anticorps Piga, anticorps piga

Sujet: The PIGA gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.Synonyms: GlcNAc-PI synthesis protein, PIG-A, Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, Phosphatidylinositol-glycan biosynthesis class A protein

ID gène: 5277

NCBI Accession: NP_002632

Pathways: Inositol Metabolic Process