PFKFB2 anticorps (AA 7-19)

N° du produit ABIN962679

Détail du produit anti-PFKFB2 anticorps

Antigène: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Épitope: AA 7-19

Reactivité: Humain, Singe

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKFB2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human PFKFB2. This antibody is expected to recognize both reported isoforms (NP_006203.2, NP_001018063.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Orangutan, Dog, Pig (92%) Bovine (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide SEQNNNSYETKTP-C from the N-terminus of human PFKFB2 (NP_006203.2, NP_001018063.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Orangutan, Dog, Pig (92%), Bovine (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (2.5 - 3.75 μg/mL), Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 75Da band in Human Heart lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 58.5  kDa according to NP_006203.2 and 54.4  kDa according to NP_001018063.1. The 75  kDa band was successfully blocked by incubation with the immunizing peptide.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur PFKFB2

Antigène: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Autre désignation: PFKFB2 (PFKFB2 Produits)

Synonymes: anticorps pfkfb2, anticorps zgc:56282, anticorps PFK-2/FBPase-2, anticorps 4930568D07Rik, anticorps RH2K, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, anticorps pfkfb2a, anticorps PFKFB2, anticorps pfkfb2, anticorps Pfkfb2

Sujet: Name/Gene ID: PFKFB2

Synonyms: PFKFB2, 6PF-2-K/Fru-2,6-P2ase 2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB, cardiac

ID gène: 5208

NCBI Accession: NP_006203, NP_001018063

UniProt: O60825

Pathways: Signalisation PI3K-Akt, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process