C-JUN anticorps

N° du produit ABIN965722

Cet anticorps Lapin Polyclonal détecte spécifiquement C-JUN dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat. Il a été cité dans 3+ publications.

Aperçu rapide pour C-JUN anticorps (ABIN965722)

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-C-JUN anticorps

Specificité: C-Jun (Ab-239) antibody detects endogenous levels of total c-Jun protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of threonine 239 (G-E-TP-P-P).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-C-JUN (ABIN965722)

Kyriakis, Banerjee, Nikolakaki, Dai, Rubie, Ahmad, Avruch, Woodgett: "The stress-activated protein kinase subfamily of c-Jun kinases." dans: Nature, Vol. 369, Issue 6476, pp. 156-60, (1994) (PubMed).

Smeal, Binetruy, Mercola, Birrer, Karin: "Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73." dans: Nature, Vol. 354, Issue 6353, pp. 494-6, (1992) (PubMed).

Boyle, Smeal, Defize, Angel, Woodgett, Karin, Hunter: "Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity." dans: Cell, Vol. 64, Issue 3, pp. 573-84, (1991) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: c-Jun

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins