C-JUN anticorps

N° du produit ABIN965724

Cité dans 4 publications. Cet anticorps anti-C-JUN Polyclonal Lapin (ABIN965724) détecte spécifiquement C-JUN dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C-JUN anticorps (ABIN965724)

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-C-JUN anticorps

Specificité: C-Jun ( Ab-63) antibody detects endogenous levels of c-Jun protein around serine 63.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 63 (L-T-SP-P-D).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-C-JUN (ABIN965724)

Wei, Jin, Schlisio, Harper, Kaelin: "The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase." dans: Cancer cell, Vol. 8, Issue 1, pp. 25-33, (2005) (PubMed).

Sevilla, Santos, Barcia, Vega, Lazo: "c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)." dans: Oncogene, Vol. 23, Issue 55, pp. 8950-8, (2004) (PubMed).

Li, Feng, Porter: "JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells." dans: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4058-65, (2004) (PubMed).

Hurd, Waldron, Rozengurt: "Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus." dans: Oncogene, Vol. 21, Issue 14, pp. 2154-60, (2002) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: c-Jun

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins