CHEK1 anticorps

N° du produit ABIN965882

1 publication est disponible pour ce produit. L’anticorps anti-CHEK1 Monoclonal produit chez le not_set a été validé pour WB et ELISA. Il convient pour la détection de CHEK1 dans des échantillons provenant de Humain. }

Aperçu rapide pour CHEK1 anticorps (ABIN965882)

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp CHEK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHEK1 anticorps

Specificité: Ni-NTA purified recombinant protein CHK1 expressed in E. Coli strain M15.

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: Dilution 1: 2,00- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-CHEK1 (ABIN965882)

OConnell, Raleigh, Verkade, Nurse: "Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation." dans: The EMBO journal, Vol. 16, Issue 3, pp. 545-54, (1997) (PubMed).

Détails sur CHEK1

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Autre désignation: CHK1

Sujet: Active recombinant full length human CHK1 containing an Nterminal GST tag. This protein has an apparent molecular weight of ~82kDa. CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia.

Pathways: Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN