FLT4 anticorps

N° du produit ABIN966155

Détail du produit anti-FLT4 anticorps

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FLT4 expressed in E. Coli.

Clone: 4H4

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-FLT4 (ABIN966155)

Zadik: "The cost of non-compliance in congenital adrenal hyperplasia." dans: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 22, Issue 12, pp. 1093-4, (2010) (PubMed).

Détails sur FLT4

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Autre désignation: FLT4 (FLT4 Produits)

Synonymes: anticorps FLT41, anticorps LMPH1A, anticorps PCL, anticorps VEGFR3, anticorps AI323512, anticorps Chy, anticorps Flt-4, anticorps VEGFR-3, anticorps Vegfr3, anticorps cb1059, anticorps fms related tyrosine kinase 4, anticorps FMS-like tyrosine kinase 4, anticorps fms-related tyrosine kinase 4, anticorps FLT4, anticorps Flt4, anticorps flt4

Sujet: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (ECis) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV).
Synonyms: PCL, FLT41, LMPH1A, VEGFR3, FLT4

Poids moléculaire: 145kDa

ID gène: 2324

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling