FYN anticorps

N° du produit ABIN966167

Il existe 1 publication pour ce produit. L’anticorps anti-FYN Monoclonal Souris est utilisé pour la détection de FYN dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour FYN anticorps (ABIN966167)

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FYN est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2H8

Détail du produit anti-FYN anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FYN expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-FYN (ABIN966167)

Lu, Zhu, Cvrljevic, Huang, Sarkaria, Ahkavan, Dang, Dinca, Plaisier, Oderberg, Lee, Chen, Caldwell, Xie, Loo, Seligson, Chakravari, Lee, Weinmann, Cloughesy, Nelson, Bergers, Graeber, Furnari, James, Cavenee, Johns, Mischel: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." dans: Cancer research, Vol. 69, Issue 17, pp. 6889-98, (2009) (PubMed).

Détails sur FYN

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Autre désignation: FYN

Sujet: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Synonyms: SLK, SYN, MGC45350

Poids moléculaire: 61kDa

ID gène: 2534

Pathways: Signalistation JAK/STAT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling