c-MET anticorps

N° du produit ABIN966571

Cet anticorps Lapin Polyclonal détecte spécifiquement c-MET dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat. Il a été cité dans 4+ publications.

Aperçu rapide pour c-MET anticorps (ABIN966571)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-c-MET anticorps

Specificité: Met (Ab-1234) antibody detects endogenous levels of total Met protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1234 (K-E-YP-Y-S).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-c-MET (ABIN966571)

Gherardi, Youles, Miguel, Blundell, Iamele, Gough, Bandyopadhyay, Hartmann, Butler: "Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 21, pp. 12039-44, (2003) (PubMed).

Onuchic, Furu, Nagasawa, Hou, Eggermann, Ren, Bergmann, Senderek, Esquivel, Zeltner, Rudnik-Schöneborn, Mrug, Sweeney, Avner, Zerres, Guay-Woodford, Somlo, Germino: "PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats." dans: American journal of human genetics, Vol. 70, Issue 5, pp. 1305-17, (2002) (PubMed).

Shiu, Bleecker: "Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 19, pp. 10763-8, (2001) (PubMed).

Hughes, da Silva, Friedman: "Ancient genome duplications did not structure the human Hox-bearing chromosomes." dans: Genome research, Vol. 11, Issue 5, pp. 771-80, (2001) (PubMed).

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: Met

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor