p53 anticorps (Tumor Protein P53)

Details for Product anti-TP53 Antibody No. ABIN966758, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Reactivité
Humain
2533
566
476
308
162
104
103
67
56
26
23
23
18
17
17
16
7
6
5
4
4
4
4
3
3
2
2
1
1
Hôte
Lapin
1480
1169
7
5
1
1
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp p53 est non-conjugé
82
81
69
51
44
38
37
32
23
23
23
20
20
20
20
20
19
19
18
18
17
16
15
14
14
14
14
14
12
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
2
2
2
Application
Immunohistochemistry (IHC)
2091
963
864
784
682
663
421
317
267
179
110
90
75
41
32
17
17
15
13
10
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
Specificité P53 (Ab-15) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmids, Primers & others p53 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation P53 (TP53 Antibody Extrait)
Pathways Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Lin, Chao, Saito, Mazur, Murphy, Appella, Xu: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." dans: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, 2005 (PubMed).

Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." dans: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, 2004 (PubMed).

Li, Zhang, Sejas, Bagby, Pang: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." dans: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, 2004 (PubMed).

Background publications Wang, Wiltshire, Wang, Mikell, Burks, Cunningham, Van Laar, Waters, Reed, Wang: "ATM-dependent CHK2 activation induced by anticancer agent, irofulven." dans: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39584-92, 2004 (PubMed).

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