p53 anticorps (Tumor Protein P53)

Details for Product anti-TP53 Antibody No. ABIN966759, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Reactivité
Humain
2533
566
476
308
162
104
103
67
56
26
23
23
18
17
17
16
7
6
5
4
4
4
4
3
3
2
2
1
1
Hôte
Lapin
1480
1169
7
5
1
1
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp p53 est non-conjugé
82
81
69
51
44
38
37
32
23
23
23
20
20
20
20
20
19
19
18
18
17
16
15
14
14
14
14
14
12
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
2
2
2
Application
Immunohistochemistry (IHC)
2091
963
864
784
682
663
421
317
267
179
110
90
75
41
32
17
17
15
13
10
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
Specificité P53 (Ab-315) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmids, Primers & others p53 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation P53 (TP53 Antibody Extrait)
Pathways Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Indications d'application WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Merrick, Zhou, Martin, Jeyarajah, Parker, Selkirk, Tomer, Borchers: "Site-specific phosphorylation of human p53 protein determined by mass spectrometry." dans: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, 2001 (PubMed).

Lu, Fisher, Bailey, Levine: "The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro." dans: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5923-34, 1997 (PubMed).

Lohrum, Scheidtmann: "Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes." dans: Oncogene, Vol. 13, Issue 12, pp. 2527-39, 1997 (PubMed).

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