P70 S6 Kinase (Ab-421) antibody detects endogenous levels of total p70 S6 Kinase protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
The antiserum was produced against synthesized phosphopeptide derived from human p70 S6 Kinase around the phosphorylation site of threonine 421 (P-R-TP-P-V).
RPS6KB1
Reactivité: Humain, Souris, Rat, Porc
WB, IHC, ELISA, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC: 1:50-1:100.
Restrictions
For Research Use only
Format
Liquid
Concentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Staub: "[Children helping children: first aid in primary school]." dans: Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege / Deutsche Gesellschaft für Sozialpädiatrie und Deutsche Gesellschaft für Kinderheilkunde, Vol. 22, Issue 11, pp. 484-5, (2005) (PubMed).
Le, Hittelman, Liu, McWatters, Li, Mills, Bast: "Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis." dans: Oncogene, Vol. 22, Issue 4, pp. 484-97, (2003) (PubMed).
Antigène
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))