Podocalyxin-Like (PODXL) anticorps

Détails pour le produit réf. ABIN966874, Fournisseur: Connectez-vous pour afficher
Antigène
  • Gp200
  • PC
  • PCLP
  • PCLP-1
  • AW121214
  • Ly102
  • Pclp1
  • podocalyxin
  • MEP21
  • PODXL
  • Gp135
  • PCLP1
  • cPCLP1
  • podxl
  • fc18d02
  • wu:fc18d02
  • Podxl
  • podocalyxin like
  • podocalyxin-like
  • PODXL
  • Podxl
  • podxl
Reactivité
Humain
304
100
87
61
2
2
2
1
1
Hôte
Souris
187
116
24
20
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Inconjugué
19
18
17
13
12
12
10
9
8
7
6
5
5
5
5
5
4
3
3
3
3
2
2
2
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
210
185
104
96
88
73
61
38
36
10
5
5
3
2
2
1
Options
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Immunogène Purified recombinant fragment of human PODXL expressed in E. Coli.
Clone 5F5
Isotype IgG1
Purification Ascitic fluid
Autre désignation PODXL (PODXL Antibody Extrait)
Sujet This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Tissue specificity: Glomerular epithelium cell (podocyte)
Synonyms: PC, PCLP, Gp200, PCLP-1, MGC138240
Poids moléculaire 49kDa
ID gène 5420
Pathways Tube Formation
Indications d'application Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Background publications Lee, Seo, Pulin, Gregory, Ylostalo, Prockop: "The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice." dans: Blood, Vol. 113, Issue 4, pp. 816-26, 2009 (PubMed).

Thomas, Schnaar, Konstantopoulos: "Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C505-13, 2009 (PubMed).

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