PRTN3 anticorps

N° du produit ABIN966909

Détail du produit anti-PRTN3 anticorps

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRTN3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibodies are purified by protein G affinity chromatography.

Immunogène: Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.

Clone: 3B4

Isotype: IgG2b

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-PRTN3 (ABIN966909)

Clin, Aubin, Parent, Ronsky, Labelle: "Biomechanical modeling of brace design." dans: Studies in health technology and informatics, Vol. 123, pp. 255-60, (2006) (PubMed).

Abdgawad, Hellmark, Gunnarsson, Westman, Segelmark: "Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism." dans: Clinical and experimental immunology, Vol. 145, Issue 1, pp. 63-70, (2006) (PubMed).

Détails sur PRTN3

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Autre désignation: Proteinase 3 (PRTN3 Produits)

Synonymes: anticorps ela2, anticorps MGC132250, anticorps ACPA, anticorps AGP7, anticorps C-ANCA, anticorps CANCA, anticorps MBN, anticorps MBT, anticorps NP-4, anticorps NP4, anticorps P29, anticorps PR-3, anticorps PR3, anticorps mPR3, anticorps proteinase 3 L homeolog, anticorps proteinase 3, anticorps prtn3.L, anticorps PRTN3, anticorps Prtn3

Sujet: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Synonyms: PRTN3, ACPA, CANCA

Poids moléculaire: 28kDa

ID gène: 5657