Transferrin Receptor anticorps

N° du produit ABIN967201

Détail du produit anti-Transferrin Receptor anticorps

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.

Purification: Purified.

Immunogène: Cell line KG1.

Clone: B349(DF1513)

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunofluorescense 10-20 micrograms/ml.
Flow cytometry: 1 micrograms/10^6 cells.
Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
Staining Procedure: This antibody can be used on frozen tissue sections only in IHC.

Commentaires:

Cellular Localization: Cell membrane.
Recommended Positive Control: Tonsil

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/ml.

Buffer: 0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Transferrin Receptor (ABIN967201)

Friden, Walus, Musso, Taylor, Malfroy, Starzyk: "Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).

Jing, Spencer, Miller, Hopkins, Trowbridge: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." dans: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: Transferrin Receptor,CD71 (TFRC Produits)

Synonymes: anticorps Trfr, anticorps LOC100219280, anticorps tfr, anticorps cd71, anticorps tfr1, anticorps trfr, anticorps CD71, anticorps T9, anticorps TFR, anticorps TFR1, anticorps TR, anticorps TRFR, anticorps p90, anticorps 2610028K12Rik, anticorps AI195355, anticorps AI426448, anticorps AU015758, anticorps E430033M20Rik, anticorps Mtvr-1, anticorps Mtvr1, anticorps transferrin receptor, anticorps TFRC, anticorps Tfrc, anticorps tfrc

Poids moléculaire: ~9095 kDa

ID gène: 7037

Pathways: Transition Metal Ion Homeostasis