TUBB3 anticorps

N° du produit ABIN967213

Détail du produit anti-TUBB3 anticorps

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human TUBB3 expressed in E. Coli.

Clone: 2E9

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-TUBB3 (ABIN967213)

Katsetos, Dráberová, Smejkalová, Reddy, Bertrand, de Chadarévian, Legido, Nissanov, Baas, Dráber: "Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells." dans: Neurochemical research, Vol. 32, Issue 8, pp. 1387-98, (2007) (PubMed).

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: TUBB3 (TUBB3 Produits)

Synonymes: anticorps CDCBM, anticorps CFEOM3A, anticorps TUBB4, anticorps beta-4, anticorps TUBB3, anticorps 3200002H15Rik, anticorps M(beta)3, anticorps M(beta)6, anticorps tubb3, anticorps tubulin beta 3 class III, anticorps tubulin, beta 3 class III, anticorps tubulin beta 3 class III L homeolog, anticorps beta-tubulin 3, anticorps tubulin beta-3 chain, anticorps beta tubulin 3, anticorps TUBB3, anticorps Tubb3, anticorps tubb3, anticorps tubb3.L, anticorps LOC100581245, anticorps tub3

Sujet: Tubulin, beta 3, also known as TUBB3. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The beta-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III beta-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III beta-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.
Synonyms: tubulin, beta 3, MC1R, TUBB4

Poids moléculaire: 50kDa

ID gène: 10381

Pathways: Dynamique des Microtubules, M Phase