TYRO3 anticorps (Extracellular)

N° du produit ABIN967224

Détail du produit anti-TYRO3 anticorps

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Épitope: Extracellular

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TYRO3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid

Immunogène: Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.

Clone: 10E11

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur TYRO3

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Autre désignation: TYRO3 (TYRO3 Produits)

Synonymes: anticorps TYRO3, anticorps brt, anticorps byk, anticorps dtk, anticorps rse, anticorps sky, anticorps tif, anticorps Xksy, anticorps MGC145734, anticorps DKFZp469I0432, anticorps LOC100231598, anticorps BYK, anticorps Dtk, anticorps RSE, anticorps Sky, anticorps Tif, anticorps Brt, anticorps REK, anticorps ksy, anticorps xksy, anticorps AI323366, anticorps Etk-2, anticorps Rse, anticorps TYRO3 protein tyrosine kinase, anticorps TYRO3 protein tyrosine kinase L homeolog, anticorps TYRO3 protein tyrosine kinase 3, anticorps TYRO3, anticorps tyro3, anticorps Tyro3, anticorps tyro3.L

Sujet: TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein: NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
Synonyms: BYK, Brt, Dtk, RSE, Sky, Tif

Poids moléculaire: 96.9kDa

ID gène: 7301

Pathways: Signalisation RTK