MAPK11 anticorps (AA 251-363)

N° du produit ABIN969276

Cité dans 2 publications. Cet anticorps anti-MAPK11 Monoclonal Souris (Clone 4H6H6) (ABIN969276) détecte spécifiquement MAPK11 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAPK11 anticorps (AA 251-363) (ABIN969276)

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPK11 est non-conjugé

Application: ELISA

Clone: 4H6H6

Détail du produit anti-MAPK11 anticorps

Épitope: AA 251-363

Fonction: MAPK11 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MAPK11 (ABIN969276)

Beardmore, Hinton, Eftychi, Apostolaki, Armaka, Darragh, McIlrath, Carr, Armit, Clacher, Malone, Kollias, Arthur: "Generation and characterization of p38beta (MAPK11) gene-targeted mice." dans: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10454-64, (2005) (PubMed).

Johnstone, Sibley, Lowen, Guilbert: "Epidermal growth factor stimulation of trophoblast differentiation requires MAPK11/14 (p38 MAP kinase) activation." dans: Biology of reproduction, Vol. 73, Issue 6, pp. 1282-8, (2005) (PubMed).

Détails sur MAPK11

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Autre désignation: MAPK11

Sujet: Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

UniProt: Q15759

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins