WNT5A anticorps

N° du produit ABIN969460

Détail du produit anti-WNT5A anticorps

Antigène: WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WNT5A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of WNT5A expressed in E. coli.

Clone: 6F2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-WNT5A (ABIN969460)

Ford, Ekström, Andersson: "Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 10, pp. 3919-24, (2009) (PubMed).

Dai, Hall, Escara-Wilke, Mizokami, Keller, Keller: "Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms." dans: Cancer research, Vol. 68, Issue 14, pp. 5785-94, (2008) (PubMed).

Détails sur WNT5A

Antigène: WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))

Autre désignation: WNT5A (WNT5A Produits)

Synonymes: anticorps hWNT5A, anticorps wnt-5A, anticorps wnt5a-B, anticorps WNT5A, anticorps 8030457G12Rik, anticorps Wnt-5a, anticorps Wnt family member 5A, anticorps Wnt family member 5A S homeolog, anticorps wingless-type MMTV integration site family, member 5a, anticorps wingless-type MMTV integration site family, member 5A, anticorps wingless-related MMTV integration site 5A, anticorps Wnt signaling ligand, anticorps WNT5A, anticorps Wnt5a, anticorps wnt5a.S, anticorps wnt5a, anticorps LOC578814, anticorps wnt5

Sujet:

Description: WNT5A: wingless-type MMTV integration site family, member 5A. Entrez Protein: NP_003383. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % , 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.

Aliases: hWNT5A

Poids moléculaire: 42.3 kDa

ID gène: 7474

HGNC: 7474

Pathways: Signalisation WNT, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation