BRD2 Protein (AA 1-455) (His tag)

N° du produit ABIN5853962

Détail du produit

Antigène: BRD2 (Bromodomain Containing 2 (BRD2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-455

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BRD2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMLQNVTP HNKLPGEGNA GLLGLGPEAA APGKRIRKPS LLYEGFESPT MASVPALQLT PANPPPPEVS NPKKPGRVTN QLQYLHKVVM KALWKHQFAW PFRQPVDAVK LGLPDYHKII KQPMDMGTIK RRLENNYYWA ASECMQDFNT MFTNCYIYNK PTDDIVLMAQ TLEKIFLQKV ASMPQEEQEL VVTIPKNSHK KGAKLAALQG SVTSAHQVPA VSSVSHTALY TPPPEIPTTV LNIPHPSVIS SPLLKSLHSA GPPLLAVTAA PPAQPLAKKK GVKRKADTTT PTPTAILAPG SPASPPGSLE PKAARLPPMR RESGRPIKPP RKDLPDSQQQ HQSSKKGKLS EQLKHCNGIL KELLSKKHAA YAWPFYKPVD ASALGLHDYH DIIKHPMDLS TVKRKMENRD YRDAQEFAAD VRLMFSNCYK YNPPDHDVVA MARKLQDVFE FRYAKMPD

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate buffered saline (  pH 7.4) containing, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: BRD2 (Bromodomain Containing 2 (BRD2))

Autre désignation: BRD2 (BRD2 Produits)

Synonymes: D6S113E Protein, FSH Protein, FSRG1 Protein, NAT Protein, RING3 Protein, RNF3 Protein, AW228947 Protein, D17H6S113E Protein, Frg-1 Protein, Fsrg-1 Protein, Fsrg1 Protein, Nat Protein, Ring3 Protein, Rnf3 Protein, mKIAA4005 Protein, brd2-a Protein, fsh Protein, fsrg1 Protein, nat Protein, ring3 Protein, rnf3 Protein, brd2 Protein, fe47f02 Protein, fi85h05 Protein, wu:fe47f02 Protein, wu:fi85h05 Protein, Ring3 protein Protein, bromodomain containing 2 Protein, bromodomain containing 2 S homeolog Protein, bromodomain containing 2a Protein, CHLREDRAFT_190116 Protein, CHLREDRAFT_150233 Protein, CHLREDRAFT_182576 Protein, CHLREDRAFT_188250 Protein, BRD2 Protein, Brd2 Protein, brd2.S Protein, brd2a Protein

Sujet: BRD2 is a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of roteins. This protein associates with transcription complexes and ith acetylated chromatin during mitosis, and it selectively binds o the acetylated lysine-12 residue of histone H4 via its two romodomains. The gene maps to the major histocompatability complex MHC) class II region on chromosome 6p21.3, but sequence comparison uggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Recombinant human BRD2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 52.8kDa (478aa)

NCBI Accession: NP_005095

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2