anti-Souris Cyclin D3 anticorps pour Immunoprecipitation

Recommended Cyclin D3 Antibody

Antigène
Cyclin D3 (CCND3) Anticorps
  • zgc:103502
  • CCND3
  • 9230106B05Rik
  • AA682053
  • AL024085
  • AW146355
  • C78795
  • cyclin D3
  • ccnd3
  • CCND3
  • Ccnd3
Épitope
C-Term
53
36
19
18
15
10
8
3
3
3
3
3
2
2
2
2
2
1
1
Reactivité
Souris
227
149
132
10
5
4
3
2
1
1
1
1
Hôte
Lapin
202
45
Clonalité
Polyclonal
Conjugué
Cet anticorp Cyclin D3 est non-conjugé
12
8
8
6
6
6
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
158
79
61
39
26
19
18
13
12
8
5
2
1
1
1
1
1
1
1
Options
N° du produit ABIN5706819
$ 598.50
Plus frais de port $45.00 et $22.60 pour carboglace
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
13.5936365 ABIN284024 FACS IHC (fro) IF IHC (p) IP WB Mouse IgG1 kappa DCS-22 0
1 ABIN609472 ICC IHC IHC (p) IP WB Mouse IgG1 0
1 ABIN264333 IHC (fro) IP WB Mouse IgG1 DCS-2-2 0
1 ABIN1839948 FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa DCS-22 0
1 ABIN1818203 IHC IHC (p) IP WB Mouse IgG1, kappa DCS-22 0
1 ABIN6739921 FACS IF IHC (p) IP WB Mouse IgG1, kappa DCS-22 0

General

Antigène Cyclin D3 (CCND3) Anticorps
Épitope C-Term
(53), (36), (19), (18), (15), (10), (8), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Reactivité Souris
(227), (149), (132), (10), (5), (4), (3), (2), (1), (1), (1), (1)
Hôte Lapin
(202), (45)
Clonalité
Polyclonal
Conjugué Cet anticorp Cyclin D3 est non-conjugé
(12), (8), (8), (6), (6), (6), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(158), (79), (61), (39), (26), (19), (18), (13), (12), (8), (5), (2), (1), (1), (1), (1), (1), (1), (1)
Fournisseur

Détail du produit anti-Cyclin D3 anticorps

Détail du antigène Cyclin D3 Information d'application Stockage Images
Attributs du produit

Synonyms: rabbit anti-Cyclin D3 antibody, G1/S-specific cyclin-D3, Ccnd3, Cyl-3

Background: Anti-Cyclin D3 antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Cyclin D3 belongs to a highly conserved cyclin family, whose members are the ultimate recipients of oncogenic signals. Cyclin D3 is a key component of the cell cycle progression machinery and induces progression through the G1 phase of the cell cycle. Cyclin D3 is expressed in nearly all proliferating cells, and shows the most broad expression pattern of all three D-type (D1-D3) cyclins. Cyclin D3 is encoded from the 6p21 chromosome region and the protein is predominantly localized in the nucleus. Once induced, cyclin D3 binds and activates its associated cyclin-dependent kinases CDK4 and CDK6. Amplification of the cyclin D3 gene and overexpression of cyclin D3 protein is seen in several human cancers. A large number of human malignancies contain lesions in pathways impacting on cyclin D3. Abnormal expression of Cyclin D3 is believed to be a driving force in several human cancers. A possible role for cyclin D3 in the malignancies of the lymphoid system is suggested by the observations that cyclin D3 gene is rearranged in several neoplastic diseases such as diffuse large B cell lymphomas or multiple myelomas. Anti-Cyclin D3 is ideal for researchers interested in Cancer Research and Immunology research.

Gene Name: Ccnd3

Purification Cyclin D3 affinity-purified antibody is directed against Cyclin D3 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from mouse, human, and bovine sources based on 100% homology for the immunogen sequence. Cross reactivity with other sources has not been determined. No reactivity was observed against Cyclin D2.
Immunogène

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal domain of mouse Cyclin D3 protein.

Immunogen Type: Peptide

Isotype IgG
Plasmids, Primers & others

Détail du antigène Cyclin D3

Détail du produit anti-Cyclin D3 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation Cyclin D3 (CCND3 Antibody Extrait)
ID gène 12445
UniProt P30282
Pathways Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process

Information d'application

Détail du produit anti-Cyclin D3 anticorps Détail du antigène Cyclin D3 Stockage Images Haut de la page
Indications d'application

Flow Cytometry Dilution: 4 μg/mL

Immunohistochemistry Dilution: 4 μg/mL

Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry, flow cytometry, and by immunoprecipitation. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 32.4 kDa in size corresponding to Cyclin D3 protein by western blotting in the appropriate stimulated tissue or cell lysate or extract. ELISA and western blot show equivalent reactivity against phosphorylated and non-phosphorylated Cyclin D3.

Western Blot Dilution: 1.0 μg/mL

Immunoprecipitation Dilution: 5 μg/mL

ELISA Dilution: 1:1000 - 1:5000

Restrictions For Research Use only

Stockage

Détail du produit anti-Cyclin D3 anticorps Détail du antigène Cyclin D3 Information d'application Images Haut de la page
Format Liquid
Concentration 1.0 mg/mL
Buffer

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride,  pH 7.2

Stabilizer: None

Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Date de péremption 12 months