Aperçu des produits pour anti-Insulin Receptor Substrate 1 (IRS1) Anticorps

Full name:: anti-Insulin Receptor Substrate 1 Anticorps (IRS1)

Chez www.anticorps-enligne.fr sont 590 Insulin Receptor Substrate 1 (IRS1) Anticorps de 31 de différents fournisseurs disponibles. De plus, nous expédions Insulin Receptor Substrate 1 Kits (45) et Insulin Receptor Substrate 1 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 667 Insulin Receptor Substrate 1 produits sont actuellement listés.

Synonymes:: G972R, HIRS-1, irs-1, IRS1, irs1-a, IRS1IRM, irsu

afficher tous les anticorps	Gène	GeneID	UniProt
	IRS1	3667	P35568
	IRS1	16367	P35569
	IRS1	25467	P35570
Afficher toutes les espèces Afficher tous les synonymes

Réactivités les plus populaires pour anti-Insulin Receptor Substrate 1 (IRS1) Anticorps

Sélectionnez vos espèces et l'application

anti-Human Anticorps:

anti-Mouse (Murine) Anticorps:

anti-Rat (Rattus) Anticorps:

Tous anti-Insulin Receptor Substrate 1 Anticorps disponible

Vous arrivez à notre recherche pré-filtrée.

Pathways pertinentes pour anti-Insulin Receptor Substrate 1 Anticorps

Regulation of Carbohydrate Metabolic Process

Plus produit pour Insulin Receptor Substrate 1 Anticorps

anti-Insulin Receptor Substrate 1 Anticorps mieux référencés

Mouse (Murine) Monoclonal IRS1 Primary Antibody pour IF, WB - ABIN968515 : Backer, Myers, Shoelson, Chin, Sun, Miralpeix, Hu, Margolis, Skolnik, Schlessinger: Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation. dans The EMBO journal 1992 (PubMed)
Show all 5 Pubmed References
Mouse (Murine) Monoclonal IRS1 Primary Antibody pour IF, WB - ABIN968514 : Kuhné, Zhao, Rowles, Lavan, Shen, Fischer, Lienhard: Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C. dans The Journal of biological chemistry 1994 (PubMed)
Show all 5 Pubmed References
Human Monoclonal IRS1 Primary Antibody pour WB - ABIN967601 : Burks, Bezerra, Le, Gallie, Browning: Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit. dans The Journal of biological chemistry 2001 (PubMed)
Show all 6 Pubmed References
Human Polyclonal IRS1 Primary Antibody pour IHC - ABIN966417 : Steppan, Wang, Whiteman, Birnbaum, Lazar: Activation of SOCS-3 by resistin. dans Molecular and cellular biology 2005 (PubMed)
Show all 4 Pubmed References
Human Monoclonal IRS1 Primary Antibody pour ICS - ABIN1177074 : Burks, White: IRS proteins and beta-cell function. dans Diabetes 2001 (PubMed)
Show all 4 Pubmed References
Human Monoclonal IRS1 Primary Antibody pour ICS - ABIN1177073 : Gual, Le Marchand-Brustel, Tanti: Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. dans Biochimie 2005 (PubMed)
Show all 4 Pubmed References
Human IRS1 Primary Antibody pour IHC - ABIN966413 : Tuncman, Hirosumi, Solinas, Chang, Karin, Hotamisligil: Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. dans Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
Show all 3 Pubmed References
Human IRS1 Primary Antibody pour IHC - ABIN966415 : Ozes, Akca, Mayo, Gustin, Maehama, Dixon, Donner: A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. dans Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
Show all 4 Pubmed References
Human Polyclonal IRS1 Primary Antibody pour IHC - ABIN966418 : Tzatsos, Kandror: Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. dans Molecular and cellular biology 2005 (PubMed)
Show all 3 Pubmed References
Human IRS1 Primary Antibody pour IHC - ABIN966414 : Kadowaki: Insights into insulin resistance and type 2 diabetes from knockout mouse models. dans The Journal of clinical investigation 2000 (PubMed)
Show all 3 Pubmed References

Plus d’anticorps contre Insulin Receptor Substrate 1 partenaires d’interaction

Human Insulin Receptor Substrate 1 (IRS1) interaction partners

Together, miR (Montrer MLXIP Anticorps)-145 mimics suppress cell proliferation by targeting and inhibiting IRS1 expression to inhibit MAPK/ERK (Montrer MAPK1 Anticorps) signaling pathways.
Data suggest that Y537S/D538G ESR1 (Montrer ESR1 Anticorps) mutant breast cancer cell lines exhibit enhanced proliferation in response to IGF1 (Montrer IGF1 Anticorps)/IGF1R (Montrer IGF1R Anticorps) signaling; mechanism involves IRS1; here, knockdown of IRS1 attenuates enhanced IGF1 (Montrer IGF1 Anticorps)/IGF1R (Montrer IGF1R Anticorps) signaling response in ESR1 (Montrer ESR1 Anticorps) mutant cells. (ESR1 (Montrer ESR1 Anticorps) = estrogen receptor 1 (Montrer ESR1 Anticorps); IGF1 (Montrer IGF1 Anticorps) = insulin like growth factor 1 (Montrer IGF1 Anticorps); IGF1R (Montrer IGF1R Anticorps) = IGF1 (Montrer IGF1 Anticorps) receptor; IRS1 = insulin receptor substrate 1)
The effect of PF may be associated with its role in inhibiting de novo lipid synthesis and in regulating the ROCK/IRS (Montrer IARS Anticorps)/Akt (Montrer AKT1 Anticorps) signalling pathways.
Gene expression for insulin receptor substrate 1 (IRS-1), protein kinase B (Akt-2) and glucose transporter 4 (GLUT-4 (Montrer SLC2A4 Anticorps)) genes were evaluated by real time PCR.
Reduced insulin receptor substrate-1 (IRS-1) staining in lung adenocarcinoma tissue microarray displayed a significant survival disadvantage, especially within the Kirsten rat sarcoma viral oncogene (Montrer RAB1A Anticorps) homolog (KRAS) mutant subgroup.
This study examined the normal regional brain expression of IRS-1 and found a significant correlation with the volumetric associated with regional atrophy in Alzheimer's disease.
Data show that MIR126 induces autophagic flux in malignant mesothelioma (MM) cells by downregulating insulin receptor substrate-1 (IRS1) and disrupting the IRS1 signaling pathway.
IRS1/beta-Catenin (Montrer CTNNB1 Anticorps) Axis Is Activated and Induces MYC (Montrer MYC Anticorps) Expression in Acute Lymphoblastic Leukemia Cells
These effects were exerted by changes on the phosphorylation of IRS-1.
Allele and genotype frequencies of rs1801278 in IRS1 showed significant differences between cases and controls for obstructive sleep apnea risk in Chinese Han population.

Mouse (Murine) Insulin Receptor Substrate 1 (IRS1) interaction partners

findings suggest that up-regulation of miR (Montrer MLXIP Anticorps)-222 followed by reduction in IRS-1 expression may be a viable mechanism of insulin (Montrer INS Anticorps) resistance in the liver
These results demonstrate the cooperative interaction between RPTPbeta (Montrer PTPRZ1 Anticorps) and the IGF-I receptor (Montrer IGF1R Anticorps) leading to a coordinated series of signaling events that are required for osteoblast differentiation. Our findings emphasize the important role IRS-1 plays in modulating these signaling events and confirm its essential role in facilitating osteoblast differentiation
EGCG significantly ameliorated insulin (Montrer INS Anticorps) resistance and cognitive disorder by up-regulating the insulin receptor substrate-1 (IRS-1)/AKT (Montrer AKT1 Anticorps) and ERK (Montrer EPHB2 Anticorps)/cAMP response element binding protein (CREB)/brain-derived neurotrophic factor (BDNF (Montrer BDNF Anticorps)) signaling pathways.
Pit1 (Montrer POU1F1 Anticorps) deletion inhibited USP7 (Montrer USP7 Anticorps)/IRS1 dissociation upon insulin (Montrer INS Anticorps) stimulation.
TSH improves insulin (Montrer INS Anticorps) sensitivity in skeletal muscle by increasing Irs1 gene expression.
Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Ialpha2 expression via miR (Montrer MLXIP Anticorps)-342
Irs1 was downregulated in the arcuate nucleus of type 2 diabetic mice.
In conclusion, we have identified that ARL15 acts as an insulin (Montrer INS Anticorps)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1/PDPK1 (Montrer PDPK1 Anticorps)/AKT (Montrer AKT1 Anticorps) insulin (Montrer INS Anticorps) pathway by interacting with its GAP ASAP2 (Montrer ASAP2 Anticorps) and activating PDPK1 (Montrer PDPK1 Anticorps). This research may provide new insights into GTPase (Montrer RACGAP1 Anticorps)-mediated insulin (Montrer INS Anticorps) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (Montrer INS Anticorps) sensitizati
These findings illuminate a new function of IRS-1: that of maintaining cells in their normal, differentiated state. Because IRS-1 is down-regulated in states of insulin (Montrer INS Anticorps) resistance that occur in response to metabolic stresses such as obesity and cytokine stimulation
Decreased miR (Montrer MLXIP Anticorps)-33 levels can up-regulate IRS-2 (Montrer IRS2 Anticorps) expression, which appears to compensate for the defects of the insulin (Montrer INS Anticorps) signaling pathway in Irs-1 deficient mice.

Rabbit Insulin Receptor Substrate 1 (IRS1) interaction partners

IRS1 gene was associated with growth traits in rabbits.Association between the IRS1 and FTO (Montrer FTO Anticorps) genes regulates body weight in rabbits.

Pig (Porcine) Insulin Receptor Substrate 1 (IRS1) interaction partners

miR (Montrer MYLIP Anticorps)-146a-5p targets porcine insulin receptor (Montrer INSR Anticorps) and could inhibit its protein expression.
TBC1D4 (Montrer TBC1D4 Anticorps), insulin receptor (Montrer INSR Anticorps) and GLUT4 (Montrer SLC2A4 Anticorps) showed altered expression in some tissues in pre-diabetic pigs.
Association analysis of genotypes with growth traits, anatomy traits, meat quality traits and physiological biochemical indexes traits showed that different genotypes at locus 3,257 of IRS-1 have significant differences in carcass straight length in pigs.

Xenopus laevis Insulin Receptor Substrate 1 (IRS1) interaction partners

Knock down of IRS-1 in neural tissue by specific antisense morpholino oligonucleotides (MO) resulted in abnormal eye formation accompanied by reduction of the eye-specific marker genes Rx1 and Pax6 (Montrer PAX6 Anticorps) and a decreased cell proliferation.

Insulin Receptor Substrate 1 (IRS1) profil antigène

Antigen Summary

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

Alternative names and synonyms associated with Insulin Receptor Substrate 1 (IRS1)

insulin receptor substrate 1 (IRS1) anticorps
insulin receptor substrate 1 (Irs1) anticorps
insulin receptor substrate 2 (irs2) anticorps
insulin receptor substrate 1 S homeolog (irs1.S) anticorps

G972R anticorps
HIRS-1 anticorps
irs-1 anticorps
IRS1 anticorps
irs1-a anticorps
IRS1IRM anticorps
irsu anticorps

Protein level used designations for IRS1

IRS-1 , pp185 , insulin receptor substrate 1 , XIRS-L , insulin receptor substrate 1-A , xIRS-1-A

GENE ID	SPECIES
3667	Homo sapiens
16367	Mus musculus
25467	Rattus norvegicus
394823	Xenopus (Silurana) tropicalis
459985	Pan troglodytes
486148	Canis lupus familiaris
538598	Bos taurus
100271862	Felis catus
100339981	Oryctolagus cuniculus
100607873	Nomascus leucogenys
100512686	Sus scrofa
100716939	Cavia porcellus
101102293	Ovis aries
399299	Xenopus laevis
101749888	Gallus gallus

Fournisseurs de qualité sélectionnés pour anti-Insulin Receptor Substrate 1 (IRS1) Anticorps

Avez-vous cherché autre chose?

Tel:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@anticorps-enligne.fr

Show all anti-Insulin Receptor Substrate 1 (IRS1) Anticorps with Pubmed References