TNFRSF11A Kit ELISA

N° du produit ABIN2042647

Détail du produit TNFRSF11A Kit ELISA

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5-4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 2 pg/mL

Ingrédients: 96-well plate pre-coated with anti-RANK, Human
Lyophilized recombinant RANK, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Human RANK in cell culture supernates and serum.Receptor Activator of Nuclear Factor B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is a recently described TNF receptor family member, and its ligand, RANKL, promote survival of dendritic cells and differentiation of osteoclasts. RANK contains 383 amino acids in its intracellular domain (residues 234-616), which contain three putative TRAF-binding domains (termed I, II, and III). RANK interacts with various TRAFs through distinct motifs and activates NF-kappaB via a novel TRAF6 interaction motif, which then activates NIK, thus leading to NF-kappaB activation, whereas RANK most likely activates JNK through a TRAF2-interacting region in RANK. The standard in this kit is recombinant human RANK with the sequence of Q29-G213 aa. It is a dipolymer which compose of two chains, and the molecular weight of each is 48kD.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Autre désignation: RANK (TNFRSF11A Produits)

Synonymes: RANK Kit ELISA, RGD1563614 Kit ELISA, TNFRSF11A Kit ELISA, Ly109 Kit ELISA, ODFR Kit ELISA, OFE Kit ELISA, Rank Kit ELISA, TRANCE-R Kit ELISA, mRANK Kit ELISA, CD265 Kit ELISA, FEO Kit ELISA, LOH18CR1 Kit ELISA, OPTB7 Kit ELISA, OSTS Kit ELISA, PDB2 Kit ELISA, TRANCER Kit ELISA, TNF receptor superfamily member 11A Kit ELISA, TNF receptor superfamily member 11a Kit ELISA, tumor necrosis factor receptor superfamily, member 11a, NFKB activator Kit ELISA, Tnfrsf11a Kit ELISA, TNFRSF11A Kit ELISA

ID gène: 4790

UniProt: P19838

Pathways: Signalisation NF-kappaB