TNFSF4 Kit ELISA

N° du produit ABIN2042706

Détail du produit TNFSF4 Kit ELISA

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5-4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 10 pg/mL

Ingrédients: 96-well plate pre-coated with anti-TNFSF4/OX40L, Mouse
Lyophilized recombinant TNFSF4/OX40L, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Mouse TNFSF4/OX40L in cell culture supernates, serum and plasma (heparin, EDTA).OX40L is the ligand for CD134 and is expressed on such cells as DC2s enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252. By analysis of an interspecific backcross, Baum et al. (1994) mapped the mouse Tnfsf4 gene to chromosome 1. Using fluorescence in situ hybridization, they localized the human TNFSF4 gene to 1q25, a region sharing homology of synteny with the portion of mouse chromosome 1 containing the Tnfsf4 gene.OX40L strongly inhibited the generation of IL-10-producing Tr1 cells induced by two physiologic stimuli, the inducible costimulatory ligand and immature dendritic cells. In addition, OX40L strongly inhibited IL-10 production and suppressive function of differentiated IL-10-producing Tr1 cells. Tnfsf4 underlies Ath1 in mice and that polymorphisms in its human homolog TNFSF4 increase the risk of myocardial infarction in humans.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Autre désignation: TNFSF4/OX40L (TNFSF4 Produits)

Synonymes: TNFSF4 Kit ELISA, OX40L Kit ELISA, TNFRSF4 Kit ELISA, CD134L Kit ELISA, CD252 Kit ELISA, GP34 Kit ELISA, OX-40L Kit ELISA, OX4OL Kit ELISA, TXGP1 Kit ELISA, Ath-1 Kit ELISA, Ath1 Kit ELISA, Ox40l Kit ELISA, Txgp1l Kit ELISA, gp34 Kit ELISA, TNF superfamily member 4 Kit ELISA, tumor necrosis factor (ligand) superfamily, member 4 Kit ELISA, TNFSF4 Kit ELISA, Tnfsf4 Kit ELISA

ID gène: 22164

UniProt: P43488

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints