TNFSF13 Kit ELISA

N° du produit ABIN5510596

Détail du produit TNFSF13 Kit ELISA

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Épitope: AA 105-250

Reactivité: Singe

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate TNFSF13/APRIL

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO,A105-L250

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Autre désignation: TNFSF13 (TNFSF13 Produits)

Synonymes: APRIL Kit ELISA, CD256 Kit ELISA, TALL-2 Kit ELISA, TALL2 Kit ELISA, TRDL-1 Kit ELISA, ZTNF2 Kit ELISA, 2310026N09Rik Kit ELISA, April Kit ELISA, Tall2 Kit ELISA, Trdl1 Kit ELISA, SLAN Kit ELISA, ANP32B Kit ELISA, april Kit ELISA, tnf13 Kit ELISA, TNLG7B Kit ELISA, TNF superfamily member 13 Kit ELISA, tumor necrosis factor (ligand) superfamily, member 13 Kit ELISA, acidic leucine-rich nuclear phosphoprotein 32 family member B Kit ELISA, TNFSF13 Kit ELISA, Tnfsf13 Kit ELISA, LOC494442 Kit ELISA, tnfsf13 Kit ELISA

Sujet:

Background: Tumor necrosis factor ligand superfamily member 13(TNFSF13) also known as a proliferation-inducing ligand(APRIL) is a protein that in humans is encoded by the TNFSF13 gene. TNFSF13 has also been designated CD256(cluster of differentiation 256). The protein encoded by this gene is a member of the tumor necrosis factor ligand(TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vivo experiments suggest an important role for APRIL in the long-term survival of plasma cells in the bone marrow. Mice deficient in April showed a reduced ability to support plasma cell survival In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such asTNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The TNFSF13 gene lies 878 bp downstream of the TNFSF12 gene on chromosome 17p13.1.

Synonyms: Tumor necrosis factor (Ligand) superfamily member 13 transcript variant delta ,Tumor necrosis factor ligand superfamily member 13 ,TNFSF13 ,

Full Gene Name: tumor necrosis factor (ligand) superfamily, member 13

UniProt: Q2QBA2

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response