CD137 Kit ELISA
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- Antigène Voir toutes CD137 (TNFRSF9) Kits ELISA
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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Reactivité
- Souris
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 31.2 pg/mL - 2000 pg/mL
- Seuil minimal de détection
- 31.2 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: 4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CDw137, Homolog of mouse 4 1BB, ILA, Induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Receptor protein 4 1BB, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9
Background: CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Gene Name: TNFRSF9
Production: Natural and recombinant mouse TNFRSF9. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: V24-L187
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL mouse TNFRSF9 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each mouse TNFRSF9 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 31.2pg/mL-2000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes CD137 (TNFRSF9) Kits ELISA
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Autre désignation
- TNFRSF9 - 4-1BB (TNFRSF9 Produits)
- Synonymes
- TNFRSF9 Kit ELISA, zgc:136557 Kit ELISA, 4-1BB Kit ELISA, CD137 Kit ELISA, CDw137 Kit ELISA, ILA Kit ELISA, A930040I11Rik Kit ELISA, AA408498 Kit ELISA, AI325004 Kit ELISA, Cd137 Kit ELISA, Ly63 Kit ELISA, tumor necrosis factor receptor superfamily member 9 Kit ELISA, TNF receptor superfamily member 9 Kit ELISA, tumor necrosis factor receptor superfamily, member 9a Kit ELISA, tumor necrosis factor receptor superfamily, member 9 Kit ELISA, TNFRSF9 Kit ELISA, tnfrsf9a Kit ELISA, Tnfrsf9 Kit ELISA
- ID gène
- 21942
- NCBI Accession
- NP_001070977
- UniProt
- P20334
- Pathways
- Cancer Immune Checkpoints
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