Osteoactivin Protéines
(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
GPNMB
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
GPNMB
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS
1 image
GPNMB
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 85 %
SDS
1 image
GPNMB
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by SDS-PAGE
1 image
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
GPNMB
Origine: Humain
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
GPNMB
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 98 % as determined by reducing SDS-PAGE.
GPNMB
Origine: Humain
Hôte: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
Origine: Humain
Hôte: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
Origine: Souris
Hôte: Mammalian Cells
Recombinant
> 90 %
Inactive
GPNMB
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Dernières publications pour nos Osteoactivin Protéines
: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." dans: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
Pseudonymes pour Osteoactivin Protéines
glycoprotein nmb (Gpnmb) Protéinesglycoprotein nmb (GPNMB) Protéines
glycoprotein (transmembrane) nmb (Gpnmb) Protéines
glycoprotein nmb L homeolog (gpnmb.L) Protéines
DC-HIL Protéines
Dchil Protéines
HGFIN Protéines
ipd Protéines
NMB Protéines
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