Osteoactivin Produits
(Osteoactivin (GPNMB))
Catégories
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories Osteoactivin en vedette
Osteoactivin Anticorps
High quality antibodies with extensive validation data.
Osteoactivin Kits ELISA
Reliable ELISA kits for a wide range of species.
Osteoactivin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Osteoactivin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (6)
- (2)
- (1)
N° du produit
ABIN749093
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
- (6)
N° du produit
ABIN1724859
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
N° du produit
ABIN523856
Quantité
100 μg
Fiche technique
Fiche technique
Osteoactivin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969089
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5564592
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN2703382
Quantité
96 tests
Fiche technique
Fiche technique
Osteoactivin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274753
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274754
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7491429
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Osteoactivin
: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." dans: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." dans: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).
: "Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells." dans: Oncotarget, Vol. 7, Issue 12, pp. 13932-44, (2017) (PubMed).
: "Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas." dans: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1761-70, (2016) (PubMed).
: "Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping." dans: BMC musculoskeletal disorders, Vol. 17, pp. 34, (2016) (PubMed).
: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
: "Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models." dans: FEBS open bio, Vol. 6, Issue 9, pp. 902-13, (2016) (PubMed).
: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).
: "Mutation in Osteoactivin Promotes Receptor Activator of NF?B Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function." dans: The Journal of biological chemistry, Vol. 290, Issue 33, pp. 20128-46, (2015) (PubMed).
: "The potential role of the glycoprotein osteoactivin/glycoprotein nonmetastatic melanoma protein B in pancreatic cancer." dans: Pancreas, Vol. 44, Issue 2, pp. 302-10, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à Osteoactivin
glycoprotein nmb (Gpnmb), glycoprotein nmb (GPNMB), glycoprotein (transmembrane) nmb (Gpnmb), glycoprotein nmb L homeolog (gpnmb.L), DC-HIL, Dchil, HGFIN, ipd, NMBProtein level used designations for Osteoactivin
- osteoactivin
- transmembrane glycoprotein NMB
- glycoprotein NMB
- glycoprotein nmb-like protein
- transmembrane glycoprotein HGFIN
- dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand
- dendritic cell-associated transmembrane protein
- iris pigment dispersion
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