anti-Rat (Rattus) Proprotein Convertase Subtilisin/kexin Type 2 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended Proprotein Convertase Subtilisin/kexin Type 2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) Anticorps
  • NEC 2
  • NEC-2
  • NEC2
  • PC2
  • SPC2
  • PCSK2
  • 6330411F23Rik
  • AI839700
  • Nec-2
  • Nec2
  • Phpp-2
  • pc2
  • nec2
  • spc2
  • pcsk2
  • pcsk2-A
  • proprotein convertase subtilisin/kexin type 2
  • proprotein convertase subtilisin/kexin type 2 L homeolog
  • PCSK2
  • pcsk2
  • Pcsk2
  • pcsk2.L
Épitope
AA 110-125, N-Term
15
8
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain, Rat (Rattus)
66
34
27
6
3
3
3
2
2
2
2
2
1
1
Hôte
Lapin
60
6
1
Clonalité
Polyclonal
Conjugué
Inconjugué
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
49
14
14
13
12
12
7
6
3
3
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Request

Recevoir ce produit gratuitement

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

Images

N° du produit ABIN3044078
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1409726 IHC (p) WB HRP Rabbit IgG AA 255-290 Connectez-vous pour afficher Polyclonal 0
1 ABIN1385997 IF (p) IHC (p) WB Rabbit IgG AA 255-290 Connectez-vous pour afficher Polyclonal 1
1 ABIN1391833 IHC (p) WB Biotin Rabbit IgG AA 255-290 Connectez-vous pour afficher Polyclonal 0
1 ABIN2626611 IHC IHC (p) WB Rabbit IgG AA 110-125 Connectez-vous pour afficher Polyclonal 0
1 ABIN3032331 IHC (p) WB Rabbit IgG N-Term Connectez-vous pour afficher Polyclonal 0

General

Antigène Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) Anticorps
Épitope AA 110-125, N-Term
(15), (8), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Rat (Rattus)
(66), (34), (27), (6), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Hôte Lapin
(60), (6), (1)
Clonalité
Polyclonal
Conjugué Inconjugué
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(49), (14), (14), (13), (12), (12), (7), (6), (3), (3), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit

Détail du antigène Information d'application Stockage Images
Fonction Rabbit IgG polyclonal antibody for Neuroendocrine convertase 2(PCSK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Séquence GYRDINEIDI NMNDPL
Réactivité croisée (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Attributs du produit Rabbit IgG polyclonal antibody for Neuroendocrine convertase 2(PCSK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: proprotein convertase subtilisin/kexin type 2
Protein Name: Neuroendocrine convertase 2
Purification Immunogen affinity purified.
Immunogène A synthetic peptide corresponding to a sequence at the N-terminus of human Proprotein Convertase 2(110-125aa GYRDINEIDINMNDPL), identical to the related mouse and rat sequences.
Isotype IgG

Détail du antigène

Détail du produit Information d'application Stockage Images Haut de la page
Antigène
Autre désignation PCSK2 (PCSK2 Antibody Extrait)
Sujet PCSK2(Proprotein Convertase, Subtilisin/Kexin-Type, 2), also known as PC2 or NEC2, is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of proinsulin to insulin intermediates. Seidah et al.(1991) mapped the NEC2 gene to human chromosome 20p11.2-p11.1. Ohagi et al.(1992) observed expression of the chloramphenicol acetyltransferase reporter fusions containing the putative promoter region in insulinoma cells but not in hepatoma cells, consistent with the known tissue-specific pattern of expression of the PC2 gene. Analysis of the level of CAT activity with several deletion mutants identified the region from -1100 to -539 from the translation start site as essential for PC2 promoter activity.

Synonyms: KEX2 like endoprotease 2 antibody|KEX2-like endoprotease 2 antibody|NEC 2 antibody|NEC2 antibody|NEC2_HUMAN antibody|Neuroendocrine convertase 2 antibody|PC2 antibody|PCSK2 antibody|Prohormone convertase 2 antibody|Proprotein convertase 2 antibody|Proprotein convertase subtilisin/kexin type 2 antibody|SPC2 antibody
UniProt P16519
Pathways Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity

Information d'application

Détail du produit Détail du antigène Stockage Images Haut de la page
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for PCSK2 is approximately 10 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Stockage

Détail du produit Détail du antigène Information d'application Images Haut de la page
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Agent conservateur Thimerosal (Merthiolate), Sodium azide
Précaution d'utilisation This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Date de péremption 12 months

Images

Détail du produit Détail du antigène Information d'application Stockage Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 110-125), (N-Term) antibody (ABIN3044078) anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 110-125), (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 110-125), (N-Term) antibody (ABIN3044078) Anti-Proprotein Convertase 2 antibody, IHC(P) IHC(P): Rat Pancreas Tissue
Western Blotting (WB) image for anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 110-125), (N-Term) antibody (ABIN3044078) Anti-Proprotein Convertase 2 antibody, Western blottingAll lanes: Anti Proprotein Con...