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SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (Middle Region) Peptide
SHC1
Reactivité: Humain
Hôte: Synthetic
WB
N° du produit ABIN5518203
Détail du produit
(cache)
Antigène
Tous les produits SHC1
SHC1
(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
Protein Region
Middle Region
Origine
Humain
Source
Toutes les hôtes sur SHC1 Peptides
Synthetic
Application
Western Blotting (WB)
Séquence
EPPDHQYYND FPGKEPPLGG VVDMRLREGA APGAARPTAP NAQTPSHLGA
Alternatives
(show)
Information d'application
(cache)
Restrictions
For Research Use only
Stockage
(cache)
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Détail du antigène
(cache)
Antigène
SHC1
(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
Synonymes
SHC1 Peptide, SHC Peptide, SHCA Peptide, P66shc Peptide, si:dkey-246i14.4 Peptide, wu:fc10h03 Peptide, shc Peptide, p66shc Peptide, Shc Peptide, ShcA Peptide, p66 Peptide, SHC adaptor protein 1 Peptide, Shc1p Peptide, squalene--hopene cyclase Peptide, SHC (Src homology 2 domain containing) transforming protein 1 Peptide, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog Peptide, src homology 2 domain-containing transforming protein C1 Peptide, SHC1 Peptide, shc1 Peptide, Shc1 Peptide, shc1.L Peptide
Sujet
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. Alias Symbols: SHC, SHCA Protein Size: 167
ID gène
6464
NCBI Accession
NM_001130040 , NP_001123512
UniProt
P29353
Vus récemment
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Peptides
SHC1
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (Middle Region) Peptide (ABIN5518203)