This is a synthetic peptide designed for use in combination with anti- CAMKK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
CAMKK2
Reactivité: Humain, Souris, Rat
Hôte: Synthetic
BP
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
CAMKK2
(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
Synonymes
CAMKK Peptide, CAMKKB Peptide, 6330570N16Rik Peptide, AW061083 Peptide, mKIAA0787 Peptide, camk2b Peptide, fj90d04 Peptide, wu:fj90d04 Peptide, si:dkey-174n20.2 Peptide, CAMKK2 Peptide, calcium/calmodulin dependent protein kinase kinase 2 Peptide, calcium/calmodulin-dependent protein kinase kinase 2, beta Peptide, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 Peptide, calcium/calmodulin dependent protein kinase II beta Peptide, calcium/calmodulin-dependent protein kinase kinase 2 Peptide, CAMKK2 Peptide, Camkk2 Peptide, camk2b1 Peptide, CAMK2B Peptide, camkk2 Peptide
Sujet
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.