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TANK-Binding Kinase 1 (TBK1) Peptide

TBK1 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937738
  • Antigène Tous les produits TBK1
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    EEETTTRHKV LIMEFCPCGS LYTVLEEPSN AYGLPESEFL IVLRDVVGGM
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of TBK1 antibody,
    Alternative Names: TBK1 control peptide, TBK1 antibody Blocking Peptide, Anti-TBK1 Blocking Peptide, Tank-Binding Kinase 1 Blocking Peptide, FLJ11330 Blocking Peptide, NAK Blocking Peptide, T2K Blocking Peptide, TBK1, TBK-1, TBK 1, TBK-1 Blocking Peptide, TBK 1 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Synonymes
    nak Peptide, t2k Peptide, TBK1 Peptide, wu:fk70c05 Peptide, zgc:136548 Peptide, NAK Peptide, T2K Peptide, 1200008B05Rik Peptide, AI462036 Peptide, AW048562 Peptide, TANK binding kinase 1 L homeolog Peptide, TANK binding kinase 1 Peptide, TANK-binding kinase 1 Peptide, tbk1.L Peptide, TBK1 Peptide, tbk1 Peptide, Tbk1 Peptide
    Sujet
    The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.
    Poids moléculaire
    84 kDa
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