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Activin A Receptor Type II-Like 1 (ACVRL1) Peptide

ACVRL1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN972889
  • Antigène Tous les produits ACVRL1
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-ACVRL1 antibody (Catalog #: ARP44199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Synonymes
    ACVRL1 Peptide, vgb Peptide, alk1 Peptide, zehn1109 Peptide, hm:zehn1109 Peptide, ACVRLK1 Peptide, ALK-1 Peptide, ALK1 Peptide, HHT Peptide, HHT2 Peptide, ORW2 Peptide, SKR3 Peptide, TSR-I Peptide, R-3 Peptide, R3 Peptide, SETHKIR Peptide, AI115505 Peptide, AI427544 Peptide, Acvrlk1 Peptide, Alk1 Peptide, activin A receptor like type 1 Peptide, activin A receptor type II-like 1 Peptide, activin A receptor, type II-like 1 Peptide, ACVRL1 Peptide, acvrl1 Peptide, Acvrl1 Peptide
    Sujet
    ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

    Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I

    Protein Interaction Partner: XIAP,ACVR2A,SNX6,TGFB1,TGFB3,TGFBR1,TGFBR2,TGFBRAP1,XIAP,SNX6,TGFB1

    Protein Size: 503
    Poids moléculaire
    55 kDa
    ID gène
    94
    NCBI Accession
    NM_000020, NP_000011
    UniProt
    P37023
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