Nuclear Receptor Co-Repressor 2 (NCOR2) Peptide
NCOR2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits NCOR2
- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NCOR2 antibody (Catalog #: ARP32463_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
- Synonymes
- CTG26 Peptide, N-CoR2 Peptide, SMAP270 Peptide, SMRT Peptide, SMRTE Peptide, SMRTE-tau Peptide, TNRC14 Peptide, TRAC Peptide, TRAC-1 Peptide, TRAC1 Peptide, N-CoR Peptide, SMRTe Peptide, NCOR2 Peptide, gb:be017685 Peptide, si:bz71m17.2 Peptide, smrt Peptide, ctg26 Peptide, smrte Peptide, trac1 Peptide, tnrc14 Peptide, trac-1 Peptide, smrte-tau Peptide, nuclear receptor corepressor 2 Peptide, nuclear receptor co-repressor 2 Peptide, NCOR2 Peptide, Ncor2 Peptide, ncor2 Peptide
- Sujet
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NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau
Protein Interaction Partner: BCL6,BIRC3,CCL3,CCND2,CHUK,IL8,PPARD,SIRT1,YWHAE,ZBTB16,CDKN2A,ESR1,RARA,AHR,AR,ARNT,BCL6,C1D,CBFA2T2,CHUK,CIR1,DDX20,ESR1,ESR2,FOS,HDAC1,HDAC10,HDAC3,HDAC4,HDAC5,HDAC7,MYBL2,MYOD1,NCOA3,NCOA6,NFKB1,NFKBIA,NR1D1,NR1H2,NR1H4,NR1I2,NR2F1,NR2F2,NR3C1,NR4A1,PML,POU2F1,PPARA,PPARD,PPARG,RARA,RARB,RARG,RBPJ,RELA,RUNX1,RUNX1T1,RXRA,RXRG,SAP30,SKIL,SNW1,SP1,SPEN,SRF,STAT5A,STAT5B,TBL1X,THRA,THRB,YWHAE,ZBTB16,AR,BCL6,CIR1,FOS,HDAC1,HDAC10,HDAC2,HDAC3,HDAC4,HDAC5,HDAC7,Hdac5,Hdac7,IKZF1,INPP5K,JUN,NCOA6,NCOR1,NFKBIA,NR3C1,NR4A1,PGR,PML,POU2F1,PPARA,PPARD,RARA,RBPJ,RELA,RUNX1T1,RXRA,SAP30,SIN3A,SMARCA4,SNW1,SPEN,SRF,TBL1X,THRB,VDR,ZBTB16
Protein Size: 2524 - Poids moléculaire
- 275 kDa
- ID gène
- 9612
- NCBI Accession
- NM_006312, NP_006303
- UniProt
- Q9Y618
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