CXCL7 Protein (AA 59-125, partial) (GST tag)

N° du produit ABIN1047528

Détail du produit

Antigène: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Type de proteíne: Recombinant

Attributs du protein: AA 59-125, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CXCL7 protéine est marqué à la GST tag.

Application: ELISA

Séquence: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDE

Attributs du produit: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Pureté: 90 %

Information d'application

Commentaires:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Conseil sur la manipulation: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Stock: -20 °C

Stockage commentaire: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Référence

Majumdar, Gonder, Koutsis, Poncz: "Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4." dans: The Journal of biological chemistry, Vol. 266, Issue 9, pp. 5785-9, (1991) (PubMed).

Détail du antigène

Antigène: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Autre désignation: Platelet basic protein (PPBP Produits)

Synonymes: 2400003M24Rik Protein, AI854500 Protein, CTAP3 Protein, CTAPIII Protein, Cxcl7 Protein, LA-PF4 Protein, LDGF Protein, MDGF Protein, NAP-2 Protein, NAP-2-L1 Protein, Scyb7 Protein, TGB Protein, TGB1 Protein, THBGB1 Protein, b-TG1 Protein, beta-TG Protein, B-TG1 Protein, Beta-TG Protein, CTAP-III Protein, CXCL7 Protein, PBP Protein, SCYB7 Protein, TC1 Protein, TC2 Protein, THBGB Protein, Nap-2 Protein, CTAPIII/NAP-2 Protein, Platelet basic protein Protein, pro-platelet basic protein Protein, scyb7 Protein, Ppbp Protein, PPBP Protein

Sujet: LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

Poids moléculaire: 34.7 kD

UniProt: P02775