beta Arrestin 1 Protein (AA 1-418) (His tag)

N° du produit ABIN1096110

Détail du produit

Antigène: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-418

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette beta Arrestin 1 protéine est marqué à la His tag.

Fonction: Recombinant Human β-Arrestin 1/ARRB1 (C-6His)

Séquence: MGDKGTRVFK KASPNGKLTV YLGKRDFVDH IDLVDPVDGV VLVDPEYLKE RRVYVTLTCA FRYGREDLDV LGLTFRKDLF VANVQSFPPA PEDKKPLTRL QERLIKKLGE HAYPFTFEIP PNLPCSVTLQ PGPEDTGKAC GVDYEVKAFC AENLEEKIHK RNSVRLVIRK VQYAPERPGP QPTAETTRQF LMSDKPLHLE ASLDKEIYYH GEPISVNVHV TNNTNKTVKK IKISVRQYAD ICLFNTAQYK CPVAMEEADD TVAPSSTFCK VYTLTPFLAN NREKRGLALD GKLKHEDTNL ASSTLLREGA NREILGIIVS YKVKVKLVVS RGGLLGDLAS SDVAVELPFT LMHPKPKEEP PHREVPENET PVDTNLIELD TNDDDIVFED FARQRLKGMK DDKEEEEDGT GSPQLNNRLE HHHHHH

Attributs du produit: Recombinant Human beta-Arrestin 1/ARRB1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Arg418) of Human ARRB1.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Autre désignation: beta-arrestin-1 (ARRB1 Produits)

Synonymes: arrb1 Protein, MGC83787 Protein, arb1 Protein, arr1 Protein, barr1 Protein, betaarr1 Protein, 1200006I17Rik Protein, AW208571 Protein, G430100A01Rik Protein, ARB1 Protein, ARR1 Protein, BARRES Protein, arrestin beta 1 Protein, arrestin, beta 1 Protein, arrestin beta 1 L homeolog Protein, beta-arrestin 1 Protein, putative beta-arrestin 1 Protein, ARRB1 Protein, arrb1 Protein, arrb1.L Protein, CpipJ_CPIJ016988 Protein, CpipJ_CPIJ017114 Protein, Smp_122900 Protein, Smp_126080 Protein, Smp_176980 Protein, Smp_152290 Protein, Arrb1 Protein

Sujet: Beta-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
Alternative Names: Beta-Arrestin-1, Arrestin Beta-1, ARRB1, ARR1

Poids moléculaire: 48.13 kDa

UniProt: P49407

Pathways: Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction