Tel:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@anticorps-enligne.fr

Biglycan (BGN) (AA 20-368) protein (His tag) Protein

BGN Origine: Humain Source: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1096134
$385.00
Plus shipping costs $45.00
local_shipping Destination: Etats-Unis
Envoi sous 4 jours ouvrables
  • Nom de la protéine
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 20-368
    Origine
    Humain
    Source
    Human Cells
    Purification/Conjugué
    Cette Biglycan protéine est marqué à la His tag.
    Fonction
    Recombinant Human Biglycan/BGN (C-6His)
    Séquence
    EQRGFWDFTL DDGPFMMNDE EASGADTSGV LDPDSVTPTY SAMCPFGCHC HLRVVQCSDL GLKSVPKEIS PDTTLLDLQN NDISELRKDD FKGLQHLYAL VLVNNKISKI HEKAFSPLRK LQKLYISKNH LVEIPPNLPS SLVELRIHDN RIRKVPKGVF SGLRNMNCIE MGGNPLENSG FEPGAFDGLK LNYLRISEAK LTGIPKDLPE TLNELHLDHN KIQAIELEDL LRYSKLYRLG LGHNQIRMIE NGSLSFLPTL RELHLDNNKL ARVPSGLPDL KLLQVVYLHS NNITKVGVND FCPMGFGVKR AYYNGISLFN NPVPYWEVQP ATFRCVTDRL AIQFGNYKKV DHHHHHH
    Attributs du produit
    Recombinant Human Biglycan is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu20-Lys368) of Human BGN fused with a polyhistidine tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Nom de la protéine
    Sub Type
    Fusionprotein
    Sujet
    Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-?. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-? on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
    Alternative Names: Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, BGN, SLRR1A
    Poids moléculaire
    40.47 kDa
    UniProt
    P21810
    Pathways
    Glycosaminoglycan Metabolic Process
Vous êtes ici: