Glutathione Synthetase Protein (GSS) (AA 2-474) (His tag)

N° du produit ABIN1096753

Détail du produit

Antigène: Glutathione Synthetase (GSS)

Type de proteíne: Recombinant

Attributs du protein: AA 2-474

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Glutathione Synthetase protéine est marqué à la His tag.

Fonction: Recombinant Human Glutathione Synthetase/GSH Synthetase (C-6His)

Séquence: ATNWGSLLQD KQQLEELARQ AVDRALAEGV LLRTSQEPTS SEVVSYAPFT LFPSLVPSAL LEQAYAVQMD FNLLVDAVSQ NAAFLEQTLS STIKQDDFTA RLFDIHKQVL KEGIAQTVFL GLNRSDYMFQ RSADGSPALK QIEINTISAS FGGLASRTPA VHRHVLSVLS KTKEAGKILS NNPSKGLALG IAKAWELYGS PNALVLLIAQ EKERNIFDQR AIENELLARN IHVIRRTFED ISEKGSLDQD RRLFVDGQEI AVVYFRDGYM PRQYSLQNWE ARLLLERSHA AKCPDIATQL AGTKKVQQEL SRPGMLEMLL PGQPEAVARL RATFAGLYSL DVGEEGDQAI AEALAAPSRF VLKPQREGGG NNLYGEEMVQ ALKQLKDSEE RASYILMEKI EPEPFENCLL RPGSPARVVQ CISELGIFGV YVRQEKTLVM NKHVGHLLRT KAIEHADGGV AAGVAVLDNP YPVLEHHHHH H

Attributs du produit: Recombinant Human Glutathione Synthetase/GSS is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Val474) of Human GSS fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Glutathione Synthetase (GSS)

Autre désignation: GSH-synthetase (GSS Produits)

Synonymes: PRNP Protein, 6835 Protein, CG32497 Protein, CG33065 Protein, CG6835 Protein, Dmel\\CG6835 Protein, F21A20.90 Protein, F21A20_90 Protein, GLUTATHIONE SYNTHETASE Protein, GSHB Protein, glutathione synthetase 2 Protein, GSHS Protein, AI314904 Protein, GS-A/GS-B Protein, gssls-a Protein, glutathione synthetase Protein, Glutathione Synthetase Protein, glutathione synthetase 2 Protein, glutathione synthetase L homeolog Protein, GSS Protein, GSH2 Protein, Tola_1250 Protein, PC1_3711 Protein, Dd586_3633 Protein, Kvar_0701 Protein, Alvin_0197 Protein, Nhal_0215 Protein, BC1002_0254 Protein, Cseg_4017 Protein, Snov_3844 Protein, Aazo_1904 Protein, M301_2613 Protein, Bresu_0515 Protein, Isop_1460 Protein, Marme_4020 Protein, Thicy_0325 Protein, Sinme_3668 Protein, Mesop_0757 Protein, Gss Protein, gss.L Protein

Sub Type: Fusionprotein

Sujet: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.
Alternative Names: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

Poids moléculaire: 53.45 kDa

UniProt: P48637

Pathways: L'effet Warburg