Kallikrein 7 Protein (KLK7) (AA 23-252) (His tag)

N° du produit ABIN1097020

Détail du produit

Antigène: Kallikrein 7 (KLK7)

Type de proteíne: Recombinant

Attributs du protein: AA 23-252

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Kallikrein 7 protéine est marqué à la His tag.

Fonction: Recombinant Human Kallikrein 7/KLK7/SCEE (C-6His

Séquence: EEAQGDKIID GAPCARGSHP WQVALLSGNQ LHCGGVLVNE RWVLTAAHCK MNEYTVHLGS DTLGDRRAQR IKASKSFRHP GYSTQTHVND LMLVKLNSQA RLSSMVKKVR LPSRCEPPGT TCTVSGWGTT TSPDVTFPSD LMCVDVKLIS PQDCTKVYKD LLENSMLCAG IPDSKKNACN GDSGGPLVCR GTLQGLVSWG TFPWGQPNDP GVYTQVCKFT KWINDTMKKH VDHHHHHH

Attributs du produit:

Recombinant Human Kallikrein 7/KLK7/SCEE (C-6His

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Kallikrein 7 (KLK7)

Autre désignation: Kallikrein 7 (KLK7 Produits)

Synonymes: Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein

Sujet: Recombinant Human Kallikrein 7 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu23-Arg253) of Human KLK7 fused with a polyhistidine tag at the C-terminus.
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.

Poids moléculaire: 26.17 kDa

UniProt: P49862

Pathways: Système du Complément