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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) (AA 23-405) protein (His tag) Protein

SERPINA6 Origine: Humain Source: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1097514
$729.93
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  • Antigène
    SERPINA6
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 23-405
    Origine
    Humain
    Source
    Human Cells
    • 23
    • 7
    • 3
    • 1
    • 1
    Purification/Conjugué
    Cette SERPINA6 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Serpin A6 /Transcortin (C-6His)
    Séquence
    MDPNAAYVNM SNHHRGLASA NVDFAFSLYK HLVALSPKKN IFISPVSISM ALAMLSLGTC GHTRAQLLQG LGFNLTERSE TEIHQGFQHL HQLFAKSDTS LEMTMGNALF LDGSLELLES FSADIKHYYE SEVLAMNFQD WATASRQINS YVKNKTQGKI VDLFSGLDSP AILVLVNYIF FKGTWTQPFD LASTREENFY VDETTVVKVP MMLQSSTISY LHDAELPCQL VQMNYVGNGT VFFILPDKGK MNTVIAALSR DTINRWSAGL TSSQVDLYIP KVTISGVYDL GDVLEEMGIA DLFTNQANFS RITQDAQLKS SKVVHKAVLQ LNEEGVDTAG STGVTLNLTS KPIILRFNQP FIIMIFDHFT WSSLFLARVM NPVLDHHHHH H
    Attributs du produit
    Recombinant Human Serpin Peptidase Inhibitor, Clade A, Member 6 /Serpin A6 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Met23-Val405) of Human Serpin A6 fused with a polyhistidine tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    SERPINA6
    Synonymes
    ep45-A, SERPINA6, AI265318, AV104445, Cbg, CBG, serpin family A member 6, serpin family A member 6 L homeolog, corticosteroid-binding globulin, serine (or cysteine) peptidase inhibitor, clade A, member 6, SERPINA6, serpina6.L, LOC490838, Serpina6
    Sub Type
    Fusionprotein
    Sujet
    Serpin Peptidase Inhibitor, Clade A, Member 6 (SerpinA6) belongs to the Serine Protease Inhibitors superfamily. SerpinA6 is synthesized in liver and has also been identified in a number of glycocorticoid responsive cells. SerpinA6 has an alpha-globulin protein with corticosteroid-binding properties. It is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency which is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
    Alternative Names: Corticosteroid-Binding Globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG
    Poids moléculaire
    43.67 kDa
    UniProt
    P08185
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